2-aminopurine (2AP) is a purine analog which is commonly used as a fluorescent probe in biochemical and molecular biology research. It is known to have structural differences compared to the naturally occurring purine nucleobase adenine. 2AP can be incorporated into DNA and RNA and is known to cause base-pairing errors and mutations. These properties make it useful for studying DNA replication, repair and transcription. 2AP has also been studied for its potential as an anticancer agent due to its ability to induce cytotoxicity in cancer cells. Additionally, 2AP is used in drug discovery research as a ligand to characterize the binding site of proteins and enzymes.
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