What is fmf-pac?

FMF-PAC stands for Familial Mediterranean Fever-Protein Amyloidosis Consortium, which is a genetic research collaboration that studies the link between Familial Mediterranean Fever (FMF) and Protein Amyloidosis (PAC). This consortium includes geneticists and clinicians from various countries and aims to identify the genetic mutations responsible for FMF and PAC.

FMF is an inherited, autosomal recessive disorder that affects people of Mediterranean descent. It causes periodic episodes of inflammation in the abdomen, chest, joints, and skin. PAC is a group of diseases caused by the buildup of abnormal proteins in various tissues, which can lead to organ damage and dysfunction.

The consortium conducts research on the genetic basis of both FMF and PAC to understand their underlying mechanisms and develop better treatments for affected individuals. They also work to improve genetic testing and diagnosis for these conditions. The consortium has published several research papers on FMF and PAC and continues to collaborate on ongoing studies.