What is phlorhizin?

Phlorhizin is a phenolic compound found in the bark of apple trees and other fruit trees such as pear and cherry. It is a natural diuretic, which means it promotes the production of urine and helps to flush out excess water and toxins from the body.

Phlorhizin is also known for its ability to lower blood glucose levels in diabetic animals and humans, by inhibiting glucose absorption in the intestine. This has led to it being used in the development of several anti-diabetic drugs, including the popular drug, metformin.

Phlorhizin has also been studied for its potential anti-inflammatory and anti-oxidant properties. It has been shown to have a protective effect on the liver and may have a role in preventing liver damage caused by alcohol and other toxins.

Despite its potential benefits, it is important to note that phlorhizin can also have some adverse effects, including gastrointestinal discomfort and increased risk of dehydration. It is therefore important to use it under the supervision of a healthcare provider.