What is placidyl?

Placidyl (Ethchlorvynol)

Placidyl, generically known as ethchlorvynol, was a nonbarbiturate sedative and hypnotic drug. It was primarily used for the short-term treatment of insomnia and to relieve anxiety.

Key Information:

• Classification: It belonged to the class of drugs known as carbamates and carbinols.
• Mechanism of Action: Placidyl acted as a central nervous system depressant, enhancing the effects of GABA (gamma-aminobutyric acid), a neurotransmitter that inhibits brain activity.
• Use: Historically prescribed for insomnia management. It was intended for short-term use, generally no more than a few weeks, due to its potential for dependence and tolerance.
• Adverse Effects: Common side effects included drowsiness, dizziness, nausea, blurred vision, and uncoordination. More serious side effects could include respiratory depression, hypotension, and allergic reactions. Overdoses were dangerous and potentially fatal.
• Abuse Potential: Placidyl had a high potential for abuse and addiction. Withdrawal symptoms could be severe, including seizures, delirium, and hallucinations.
• Availability: Placidyl is no longer widely available due to its safety profile and the availability of safer alternatives. Its production and prescription have significantly decreased or been discontinued in many regions.
• Discontinuation: Due to safety concerns and potential for abuse, it's been largely replaced by newer medications with fewer side effects and lower addiction potential.