Proctolin is a neuropeptide that is found in many species, including crustaceans, insects, and some mollusks. It was first discovered in the hindgut of insects, where it was shown to be an important regulator of hindgut contractions.
Proctolin is known to have a number of physiological effects, including the stimulation of muscle contraction and the modulation of neural activity. In crustaceans, proctolin has been shown to play a role in the regulation of feeding behavior and the control of the circadian rhythm.
Proctolin is typically synthesized and released by specific neurons in the central and peripheral nervous system. Its effects are mediated by specific receptors that are expressed on the target cells.
Because of its widespread distribution and physiological effects, proctolin has been the subject of extensive research in a number of fields, including neuroscience and pharmacology. It is also of interest to scientists studying the evolution of neuropeptides and their role in the regulation of behavior and physiology.
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