What is progeriya?

Progeria is a rare genetic disorder that causes rapid aging in children, leading to premature death at an average age of 14. It affects about 1 in 18 million newborns and occurs due to a mutation in the LMNA gene, which produces a protein called lamin A. This mutation causes a buildup of the abnormal protein called progerin in the body, which damages cells and tissues, leading to various health problems. Progeria is characterized by symptoms such as hair loss, wrinkled skin, growth failure, joint stiffness, and cardiovascular problems. There is no cure for progeria, and treatment aims to manage symptoms and improve quality of life. Clinical trials are underway to test potential treatments such as farnesyltransferase inhibitors, which have shown promising results in slowing the aging process in animal models.