What is pseudodominant?

Pseudodominant is a term used in genetics to describe a genetic condition that appears to be dominant but is actually caused by the interaction of more than one gene or genetic factor. In other words, individuals who appear to be homozygous for a recessive trait may display the dominant phenotype due to the effects of other genes or environmental factors.

Pseudodominance is most commonly observed in cases where two individuals who are carriers of a recessive trait have children together. If both parents transmit their recessive alleles to their offspring, the children will display the recessive phenotype, even though only one of their parents exhibits the trait. This can make the condition appear to be dominant, even though it is caused by the inheritance of two recessive alleles.

Pseudodominance can be challenging to diagnose, as it requires a thorough analysis of an individual's genetic makeup and family history. In some cases, genetic testing may be necessary to determine the underlying cause of the condition. Understanding the mechanisms behind pseudodominance is essential for accurate genetic counseling and family planning.