What is siclemia?

Sickle cell anemia, also known as sickle cell disease, is a genetic blood disorder that affects the shape and function of red blood cells. The inherited disease is caused by a mutation in the hemoglobin gene that causes red blood cells to form a crescent or sickle shape instead of the normal round shape. These abnormal cells can block blood flow, causing pain and organ damage.

Sickle cell anemia is more common among people with African ancestry, but it also occurs among people of Hispanic, Middle Eastern, and Mediterranean descent. The disease can be diagnosed through a blood test, and treatment may include blood transfusions, pain management, bone marrow transplants, and gene therapy.

People with sickle cell anemia may experience a range of symptoms, including fatigue, frequent infections, jaundice, shortness of breath, strokes, and swelling in the hands and feet. The severity of the disease varies from person to person, with some experiencing milder symptoms and others requiring more extensive medical intervention. Regular medical check-ups and management of symptoms can help improve quality of life for those with sickle cell anemia.