Spermidine is a natural polyamine compound found in all living organisms. It was first isolated in 1923 from semen and is named from the Greek word "sperma" meaning "seed".
Spermidine plays an important role in numerous biological processes including cell growth, apoptosis (programmed cell death), and gene expression. It is also known to have antioxidant properties and can protect against cellular damage caused by free radicals.
Recent research has shown that spermidine can increase the lifespan of various organisms, including rodents and flies. This may be due to its ability to induce autophagy (cellular self-cleansing), which removes damaged cells and proteins from the body.
Spermidine is found in a variety of foods, including wheat germ, soybeans, spinach, and mushrooms. It is also available as a dietary supplement. However, more research is needed to fully understand the potential health benefits and risks of supplementing with spermidine.
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