What is biacore?

Biacore is a brand of surface plasmon resonance (SPR) biosensors developed by the company Biacore, now owned by Cytiva. SPR technology is used for real-time monitoring of biomolecular interactions, allowing researchers to study binding kinetics, affinity, and specificity of protein-protein, protein-peptide, protein-small molecule, and protein-nucleic acid interactions.

Biacore instruments are commonly used in drug discovery, protein engineering, and basic research in fields such as molecular biology, biochemistry, and pharmaceutical development. The system consists of a sensor chip with immobilized ligands, a microfluidics system for sample delivery, and a detector for monitoring changes in surface interactions.

The Biacore technology enables label-free, real-time monitoring of interactions, providing quantitative data on the kinetics and thermodynamics of binding events. This information is valuable for understanding molecular recognition processes, optimizing drug candidates, and studying biomolecular interactions in physiological conditions.

Overall, Biacore instruments are widely used in academic, biotechnology, and pharmaceutical research laboratories for studying biomolecular interactions and accelerating drug discovery and development processes.