What is tmb?

"TMB" could refer to a number of different things depending on the context. Here's some information on various TMBs:

1. Total Molecular Burden (TMB) in Cancer Genomics: In the field of cancer research, TMB refers to Tumor Mutational Burden, which is a measure of the number of mutations within a tumor genome. It's used as a biomarker to predict how well a patient may respond to certain immunotherapies. High TMB can suggest that a tumor might respond better to immune checkpoint inhibitors because there's a higher likelihood of neoantigen formation.

2. TMB Bank: TMB Bank, now merged with Thanachart Bank to form TMBThanachart Bank or TTB, is a major bank in Thailand. It offers a range of financial services and products, including savings and checking accounts, loans, investment options, and more.

3. Transports Metropolitans de Barcelona (TMB): This is the main public transit operator in Barcelona, Spain, providing metro and bus services in the metropolitan area. It's an essential part of Barcelona's public transport infrastructure, serving millions of passengers annually.

4. Teatro Massimo Bellini (TMB): An opera house located in Catania, Italy, named after the composer Vincenzo Bellini. Known for its excellent acoustics and beautiful architecture, it hosts a variety of operatic and cultural performances.

5. TMB in Construction and Machinery: TMB can also stand for Tunnel Boring Machine, which is used in the excavation of tunnels. These machines are essential in large infrastructural projects requiring underground passageways.

6. The Mountain Between Us (TMB): A novel by Charles Martin, which was also adapted into a film. The story involves themes of survival and romance as two strangers get stranded in the wilderness after a plane crash.

If you have a specific context or industry in mind, please let me know, and I can provide more targeted information!