What is us221?

US221 is a major north-south highway in the southeastern United States. It starts from Perry, Florida and terminates in Lynchburg, Virginia. The total length of the highway is approximately 680 miles (1095 km). The highway passes through major cities such as Spartanburg in South Carolina and Roanoke in Virginia. It also intersects with several major highways such as I-95, I-85, I-40, I-77, and I-64. US221 is an important route for both commercial and recreational traffic, providing access to several tourism hotspots in the region like the Blue Ridge Parkway and Pisgah National Forest. The highway is designated as a "Principal Arterial" by the Federal Highway Administration, indicating its importance as a major transportation route in the US.