Kanna, scientifically known as Sceletium tortuosum, is a succulent plant native to South Africa. It has a long history of traditional use by the Khoikhoi and San people as a mood-altering substance.
Traditional Use: Historically, the Khoikhoi and San chewed, smoked, or snuffed fermented Sceletium plant material for its mood-enhancing and stress-relieving properties. It was used during ceremonies, hunting expeditions, and social gatherings to promote relaxation, sociability, and mental clarity. The traditional preparation involves fermenting the plant material.
Effects: Kanna is reported to have various effects, including:
Active Compounds: The primary active alkaloids in Sceletium tortuosum are:
These alkaloids are believed to act as serotonin reuptake inhibitors (SSRIs). https://www.wikiwhat.page/kavramlar/Serotonin%20reuptake%20inhibitors%20(SSRIs) They may also have mild PDE4 inhibitory activity.
Dosage varies depending on the form and individual sensitivity. It is essential to start with a low dose and gradually increase as needed.
It is crucial to avoid combining kanna with other substances, especially SSRIs, MAOIs, or other psychoactive drugs, due to the risk of serotonin syndrome. https://www.wikiwhat.page/kavramlar/Serotonin%20syndrome Consult with a healthcare professional before using kanna, especially if you have any underlying health conditions or are taking medications.
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